Anavex 2-73 CAS NO.195615-84-0
- FOB Price: USD: /Gram Get Latest Price
- Min.Order: 100 Milligram
- Payment Terms: T/T
- Available Specifications:
Reagent Grade(1-10)Gram
- Product Details
Keywords
- Anavex 2-73
- 195615-84-0
- Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride
Quick Details
- ProName: Anavex 2-73
- CasNo: 195615-84-0
- Molecular Formula: C19H23NO.HCl
- Application: Mixed σ1 and muscarinic receptor agon...
- DeliveryTime: on depending
- PackAge: 1g,5g,10g,100g,1000g,
- Port: Tianjin
- ProductionCapacity: 1 Kilogram/Week
- Purity: More than 98%
- Storage: Store at -20°C
- Transportation: by sea or by air
- LimitNum: 100 Milligram
- Valid Period: 2 years
Superiority
Best quality & Attractive price & Professional service;
Kailiqi Biopharma is leading by professional teams for years and is qualified as the superior supplier of Merck, Novartis, Mitsui Chemicals.
Kailiqi Biopharma develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED materials & OLED intermediates and other fine chemicals.
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Details
σ1 agonist (IC50 = 860 nM); also displays affinity for muscarinic M1-M4 receptors (Ki values < 500 nM), but not for σ2 receptors. Exhibits neuroprotective effects, prevents tau hyperphosphorylation, and attenuates scopolamine- and (+)-MK 801-induced learning deficits in a mouse model of amyloid toxicity.
References are publications that support the products' biological activity.
Villard et al (2010) Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand ANAVEX2-73, a novel aminotetrahydrofuran derivative. J.Psychopharmacol. 25 1101 PMID: 20829307
Lahmy et al (2013) Blockade of tau hyperphosphorylation and Aβ1-42 generation by the aminotetrahydrofuran derivative ANAVEX2-73, a mixed muscarinic and σ1 receptor agonist, in a nontrans Neuropsychopharmacology 38 1706 PMID:
Kailiqi Biopharma is a professional manufacturer specialized in the production and distribution of active pharmaceutical ingredients and intermediates.. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED materials & OLED intermediates and other fine chemicals. Kailiqi Biopharma consists a team of professional analytical department complete QC&QA under strict SOPs, experienced sale and after-sale service, efficient logistic support.
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1.High pressure hydrogenation
2. Low temperature reactions (-90°C)
3. Chiral compounds by asymmetric synthesis (either chiral auxiliaries or catalysts)
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